A metabolic age of 61 vs chronological 54 means your body is metabolising like someone 7 years older. This is driven by elevated body fat. With targeted interventions, this gap can close rapidly — many clients see 3–5 years improvement in just 12 weeks.
49.7 kg of muscle mass is excellent for a woman of your age and height. Average for women aged 50–59 is around 35–42 kg. This is a real strength — protecting this muscle while losing fat is the key to success with Mounjaro.
At 38.1%, body fat is above the desirable range of 24–36%. However, this is fairly typical for perimenopausal women where hormonal changes drive fat accumulation. Your HRT and Mounjaro together will help address this directly.
A rating of 9 is within the healthy range (1–12). This is positive news — it means your internal organ fat is well controlled despite the elevated subcutaneous fat. Your sarcoidosis treatment and renal considerations make keeping this low especially important.
At 31.8 (Obese Class I), this is the headline number that improves fastest with weight loss. A 10 kg loss would bring BMI to ~27.5 (overweight), and reaching 67 kg target would bring it to ~25.2 — almost healthy range. Mounjaro typically delivers 10–15% weight loss.
2.7 kg bone mass is good for your age, especially given prednisolone use which can reduce bone density. Maintaining weight-bearing exercise and adequate calcium/vitamin D intake is essential given your medication profile. Your Evorel patches also help protect bone.
49.7 kg of muscle at age 54 puts you in the top 15% of women your age. This is your biggest asset. Many women starting GLP-1 medication lose muscle alongside fat. With your strong base and the right training programme, we can ensure you lose fat while preserving (or even building) this muscle. This is the difference between looking "smaller" and looking genuinely transformed.
Your body is metabolising 7 years older than your real age. This is largely driven by the elevated body fat percentage. The exciting news? Metabolic age responds fastest to body composition changes. Clients who reduce body fat by 5–6% typically see a 5–8 year drop in metabolic age. Getting your metabolic age below 54 is a realistic 6-month target.
Your sarcoidosis history, kidney function at 60%, and current medications (prednisolone, methotrexate, bisoprolol) all influence how we approach your training and nutrition. Low-impact resistance training protects joints while building strength. Your fatigue and exercise intolerance mean we need smart programming — shorter, more effective sessions rather than marathon workouts.
Your Evorel patches, Utrogestan, and Vagifem address the hormonal changes driving perimenopausal fat accumulation. Adding Mounjaro creates a powerful combination: HRT stabilises hormones and protects bone density, while Mounjaro targets appetite regulation and insulin sensitivity. Together, they address the root causes rather than just the symptoms.
Your angina diagnosis and moderate cardiac impairment on ECHO mean cardiovascular health is paramount. The good news: GLP-1 agonists have been shown to reduce cardiac arrest risk by 22% and heart failure by 11% in major studies. Weight loss itself will reduce cardiac workload. Your bisoprolol and candesartan are already protecting your heart and kidneys.
Despite elevated overall body fat, your visceral fat rating of 9 is healthy. This is actually unusual and positive — it means your fat is predominantly subcutaneous (under the skin) rather than around your organs. Subcutaneous fat responds very well to GLP-1 medication and lifestyle changes. This is genuinely good news for your metabolic health outlook.
Caroline, your scan reveals a story of two halves. Your muscle mass is exceptional (top 15%), your visceral fat is healthy, and your bone density is good despite prednisolone use. But elevated body fat (38.1%), a metabolic age 7 years above your actual age, and BMI in the obese category are pulling your overall score down. The great news? These are exactly the metrics that respond best to the interventions we're putting in place. With Mounjaro, optimised HRT, and the right exercise programme, a B+ grade within 6 months is very achievable.
Start Mounjaro at 2.5mg. Begin tracking body composition changes with regular scans. Establish baseline bloods (cholesterol, lipids, HbA1c, kidney function, LFTs, thyroid). Begin gentle resistance training 2–3x per week focusing on muscle preservation. Increase protein intake to 1.6g/kg body weight.
Mounjaro dose increase to 5mg (if tolerated). Introduce structured exercise plan tailored to your energy levels and cardiac considerations. Focus on low-impact resistance + walking. Repeat body composition scan at week 8 to track muscle vs fat changes. Optimise nutrition based on blood test results.
Continued Mounjaro with dose adjustments as needed. Introduce advanced health testing: methylation analysis to understand your unique genetic response to exercise and nutrition, plus GlycanAge testing to measure biological ageing at a cellular level. Comprehensive blood panel to assess improvements. Build your personalised health dashboard.
Reach target weight zone (67–70 kg). Metabolic age should be at or below chronological age. Full health dashboard populated with bloods, body composition trends, genetics insights, personalised nutrition and exercise plans, sleep optimisation, and stress management. Transition from fat loss to long-term health maintenance and optimisation.
You've probably seen the headlines about "Ozempic face" and "Ozempic body" — people who lose weight rapidly on GLP-1 medications but end up looking gaunt, with sagging skin, hair thinning, and accelerated facial ageing. This happens when people lose muscle and bone density alongside fat, without any strategy to protect what matters.
With your current muscle mass of 49.7 kg (top 15% for your age), you have an incredible foundation. Our job is to make sure you keep every gram of that muscle while the fat comes off. That's the difference between looking "smaller but older" and looking genuinely healthier, stronger, and more vibrant.
This is exactly why we recommend the methylation and blood testing — it's not optional extras, it's the roadmap that prevents you falling into the GLP-1 trap.
This body composition analysis is just the starting point. We're building a comprehensive health intelligence platform for our clients that brings together all of your health data in one place — giving you a complete picture of your health and a clear roadmap to optimise it.